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MOUNT SINAI LIVER CANCER PROGRAM. 17th ANNIVERSARY. “LIVER CANCER: UPDATED REVIEW OF CLINICAL MANAGEMENT AND TRANSLATIONAL SCIENCE”


MOUNT SINAI LIVER CANCER PROGRAM. 17th ANNIVERSARY.  “LIVER CANCER: UPDATED REVIEW OF CLINICAL MANAGEMENT AND TRANSLATIONAL SCIENCE” Banner

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Add to Calendar MOUNT SINAI LIVER CANCER PROGRAM. 17th ANNIVERSARY. “LIVER CANCER: UPDATED REVIEW OF CLINICAL MANAGEMENT AND TRANSLATIONAL SCIENCE” 12/16/2022 8:30:00 AM 12/16/2022 4:30:00 PM America/New_York For More Details: https://mssm.cloud-cme.com/livercancer2022 Description: There has been a revolution in the landscape of therapies for liver cancer, both in hepatocellular carcinoma (HCC) and in cholangiocarcinoma (CCA). Targeted physicians are not aware of the impact of new therapies in HCC and CCA in the clinical practice. There is a need to educated clinicians on the landcape of therapies available and the sequencing to be used. In addition, they should be educated on the cutting-edge re... Leon & Norma Hess Center for Science and Medicine, Davis Auditorium, 1470 Madison Avenue false MM/DD/YYYY


Date & Location
Friday, December 16, 2022, 8:30 AM - 4:30 PM, Leon & Norma Hess Center for Science and Medicine, Davis Auditorium, 1470 Madison Avenue, New York, NY

Target Audience
Specialties - Academic/Research, Gastroenterology, Hematology, Hepatology, Internal Medicine, Liver Diseases, Multiple Specialties, Nurse Practitioner, Nursing, Oncology, Pathology, Physician Assistant, Primary Care Physician, Radiation Oncology, Radiology, Surgeon

Course Overview
There has been a revolution in the landscape of therapies for liver cancer, both in hepatocellular carcinoma (HCC) and in cholangiocarcinoma (CCA). Targeted physicians are not aware of the impact of new therapies in HCC and CCA in the clinical practice. There is a need to educated clinicians on the landcape of therapies available and the sequencing to be used. In addition, they should be educated on the cutting-edge research in liver cancer, particularly regarding new insights in the pathogenesis of the disease and new molecular and immune therapies. The program aims to both increase the knowledge and competence of the attendees along with improving the scientific insight on the understanding of the molecular basis of these lethal diseases based on recent discoveries. The meeting is intended to provide a summary of advances in science and clinical management of liver cancer, including the research conducted in Mount Sinai.


Objectives
  1. Review the molecular pathogenesis and target for therapies in HCC and CCA.
  2. Review the current role of surgical and loco-regional treatments for liver cancer.
  3. Critical analysis of molecular and immunotherapies in the management of advanced HCC
  4. Assess cutting edge science conducted at the Mt Sinai Liver Cancer Program-2022

Registration
Registration Fee: $25.00

Accreditation
The Icahn School of Medicine at Mount Sinai is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Credits
AMA PRA Category 1 Credits™ (6.50 hours)

Discounted sleeping rooms can be reserved with our Housing Manager, Denise Newman, Cell/Text: 347-236-7181 Phone:718-835-4911; email: [email protected]

It is the policy of the Icahn School of Medicine at Mount Sinai to ensure objectivity, balance, independence, transparency, and scientific rigor in all CME-provided educational activities. All faculty participating in the planning or implementation of a provided activity are expected to disclose to the audience any relevant financial relationships and to assist in resolving any conflict of interest that may arise from the relationship. Presenters must also make a meaningful disclosure to the audience of their discussions of unlabeled or unapproved drugs or devices. This information will be available as part of the course material.

Mitigation of Relevant Financial Relationships


Icahn School of Medicine at Mount Sinai adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including faculty, planners, reviewers or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Elisa Arceci, PhD
Mount Sinai
New York, NY
Marina Barcena Varela, PhD
Ichan School of Medicine at Mount Sinai Hospital
New york, NY
Faculty Photos
Michael Buckstein, MD
Associate Professor
Icahn School of Medicine at Mount Sinai
New York, NY
Sarah Cappuyns, MD
Mount Sinai Medical School
New York City, NY
Faculty Photos
Scott L. Friedman, MD
Fishberg Professor of Medicine, Liver Diseases and Pharmacological Sciences
Icahn School of Medicine a Mount Sinai
New York, NY
Pauline Hamon, PhD, Immunologist
Icahn School of Medicine at Mount Sinai
New York, NY
Mathias Heikenwaelder, MD, PhD
Professor and-Department Head, Chronic Inflammation and Cancer
German Cancer Research Center ((Deutsches Krebsforschungszentrum, DKFZ)
Heidelberg, Germany
Faculty Photos
Edward Kim, MD
Director of Interventional Oncology, Professor of Radiology and Surgery
Icahn School of Medicine at Mount Sinai
New York, NY
Faculty Photos
Josep M. Llovet, MD, PhD
Associate Professor of Medicine, Liver Diseases
Icahn School of Medicine at Mount Sinai
New York, NY
Faculty Photos
Amaia Lujambio, PhD
Associate Professor of Medicine, Liver Sciences, Oncological Sciences
Icahn School of Medicine at Mount Sinai
New York, NY
Faculty Photos
Thomas Marron, MD
Director, Early Phase Trials Unit, Tisch Cancer Institute, Department of Hematology and Medical Oncology
The Mount Sinai Hospital
New York, NY
Faculty Photos
Ramon Parsons, MD
Director, Tisch Cancer Institute, Ward-Coleman Chair in Cancer Research, Director, Mount Sinai Cancer
Mount Sinai Health System
New York, NY
Alexander Rialdi, PhD
Postdoc
Mount Sinai
New York, NY
Faculty Photos
Myron E. Schwartz, MD
Clinical Director, Mount Sinai Liver Cancer Program, Director of Liver Surgery, Recanati/Miller Transplantation Institute
The Mount Sinai Hospital
New York, NY
Faculty Photos
Daniela Sia, MD
Assistant Professor of Medicine, Liver Diseases
Icahn School of Medicine at Mount Sinai
New York, NY
Bachir Taouli, MD
Professor, Department of Radiology, Translational and Molecular Imaging Institute (TMII)
Icahn School of Medicine at Mount Sinai
New York, NY
Faculty Photos
Swan N. N. Thung, MD
Professor, Pathology, Molecular & Cell Based Medicine
Icahn School of Medicine at Mount Sinai
New York, NY
Faculty Photos
Augusto Villanueva, MD, PhD
Associate Professor, Liver Diseases, Hematology and Medical Oncology
Icahn School of Medicine at Mount Sinai
New York, NY
Faculty Photos
Samuel Waxman, MD
Distinguished Service Professor of Medicine, Hematology and Medical Oncology
Icahn School of Medicine at Mount Sinai
New York, NY
Chittampalli Yashawini, MD/PhD Candidate
ISMMS
New York, NY

Friday, December 16, 2022

Registration
8:30AM - 9:00AM
Welcome and Opening
9:00AM - 9:10AM
Ramon Parsons, MD
Achievements of Mount Sinai Liver Cancer Program 2005-2022
9:10AM - 9:40AM
Josep M. Llovet, MD, PhD
HANS POPPER LECTURE: Introduction
9:40AM - 10:20AM
Josep M. Llovet, MD, PhD
Inflammation, NASH and HCC
9:40AM - 10:20AM
Mathias Heikenwaelder, MD, PhD
Coffee Break
10:20AM - 10:40AM
Early Liver Cancer
10:40AM - 12:00PM
Myron E. Schwartz, MD
Molecular Pathology of HCC
10:40AM - 11:00AM
Swan N. N. Thung, MD
Imaging for Early Detection of HCC
11:00AM - 11:20AM
Bachir Taouli, MD
How Surgical Approaches Might Change with Neoadjuvant/Adjuvant Immunotherapy in HCC
11:20AM - 11:40AM
Myron E. Schwartz, MD
SBRT Approaches for Early HCC
11:40AM - 12:00PM
Michael Buckstein, MD
Lunch Break
12:00PM - 12:30PM
Intermediate and Advanced Liver Cancer
12:30PM - 2:00PM
Josep M. Llovet, MD, PhD
Role of TARE in the Management of HCC
12:30PM - 12:50PM
New Flowchart for Molecular and Immune Therapies for Advanced HCC
12:50PM - 1:10PM
Josep M. Llovet, MD, PhD
Update on Biomarkers of Response to Systemic Therapies
1:10PM - 1:30PM
Augusto Villanueva, MD, PhD
First in Human Trials for Neoadjuvant and Advanced Liver Cancer
1:30PM - 2:00PM
Thomas Marron, MD
Coffee Break
2:00PM - 2:20PM
Flash Communications from Young Investigators
2:00PM - 2:35PM
Scott L. Friedman, MD
Microbiome and HCC
2:00PM - 2:05PM
Marina Barcena Varela, PhD
Translating Single-Cell to Bulk TNA Sequencing Data to Identify Responders to Checkpoint Inhibition in Advanced Hepatocellular Carcinoma
2:05PM - 2:10PM
Sarah Cappuyns, MD
Cell-based Therapy of NASH/HCC
2:10PM - 2:15PM
Chittampalli Yashawini, MD/PhD Candidate
Macrophage Diversity in Hepatocellular Carcinoma
2:15PM - 2:20PM
Pauline Hamon, PhD, Immunologist
Targeting PRMT5 in Hepatocellular Carcinoma
2:20PM - 2:25PM
Elisa Arceci, PhD
Primary Results from the Phase 3 LEAP-002 Study: Lenvatinib Plus Pembrolizumab Versus Lenvatinib as First-line Therapy for Advanced Hepatocellular Carcinoma
2:25PM - 2:35PM
Josep M. Llovet, MD, PhD
Discussion
2:35PM - 2:45PM
Pathogenesis and Novel Targets for Therapies
2:45PM - 4:05PM
Samuel Waxman, MD
Mechanisms of Advanced Fibrosis and Implications for HCC
2:45PM - 3:05PM
Scott L. Friedman, MD
Notch, a Novel Immune Escape Mechanism in HCC
3:05PM - 3:25PM
Amaia Lujambio, PhD
Drug Discovery for Targeting Wnt Signaling in HCC
3:25PM - 3:45PM
Alexander Rialdi, PhD
Cholangiocarcinoma: Assessing Drug Combinations with Checkpoint Inhibitors
3:45PM - 4:05PM
Daniela Sia, MD
Closing Remarks
4:05PM - 4:15PM

We gratefully acknowledge the support of the following who have made this activity possible:

Exelixis, Eisai, AstraZeneca, Glycotest

Exelixis, Eisai, AstraZeneca, Glycotest

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